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Estimation of pairwise sequencesimilarity of mammalian enhancers with word neighbourhood counts.
PubMed
Göke, Jonathan; Schulz, Marcel H; Lasserre, Julia; Vingron, Martin
2012-03-01
The identity of cells and tissues is to a large degree governed by transcriptional regulation. A major part is accomplished by the combinatorial binding of transcription factors at regulatory sequences, such as enhancers. Even though binding of transcription factors is sequence-specific, estimating the sequencesimilarity of two functionally similar enhancers is very difficult. However, a similarity measure for regulatory sequences is crucial to detect and understand functional similarities between two enhancers and will facilitate large-scale analyses like clustering, prediction and classification of genome-wide datasets. We present the standardized alignment-free sequencesimilarity measure N2, a flexible framework that is defined for word neighbourhoods. We explore the usefulness of adding reverse complement words as well as words including mismatches into the neighbourhood. On simulated enhancer sequences as well as functional enhancers in mouse development, N2 is shown to outperform previous alignment-free measures. N2 is flexible, faster than competing methods and less susceptible to singl
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List of Candidates Who Passed the July 2018 Bar Exam
ALM Media
Updated
Following is the list issued by the State Board of Law Examiners of the names of the candidates who passed the bar examination given on July 25 and 26. Of the 9,679 candidates who took the exam, 63 percent were certified for admission to the bar and are to be interviewed by appropriate Committees on Character and Fitness. Copies of this list can be obtained by contacting ALM Reprints at 877-257-3382 or by visiting http://www.law.com/jsp/reprints/index.jsp.
AARON , MELODY
AARONSON , LEAH F.
ABADI , DANIELA ALEXANDRA
ABARCA , ANDREA CHRISTINA
ABBOT , GEOFFREY ALAN RENE
ABBOUD , ALICIA MARIE
ABBOUD , TYLER DANIEL
ABDELKADER , OMAR A.
ABDULRAZZAK , AMINA
ABE , KENJIRO
ABEYRATNE , KENNETH GIHAN
ABHYANKAR , SMRUTI
ABIJAOUDE , PAULINE
ABNER , MEGAN JOY
ABOAGYE , AKUA OHENETWENE
ABOUELMAATY , MERNA
ABRAHAM , FINNEY
ABRAMS , JONATHAN JEFFREY
ABRAMS-DOWNEY , STEPHEN PADDOCK
ABRAMSON , MICHAEL DAVID
ABREU , SHAUN
ABREU DE LIMA , RAMON
ABRUNZO , CALLA ANNE
ABUDU , OLAWALE MUSTAPHA
ABUHOFF , ELYSSA EDEN
ABULAFI , AMIRA
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